Jim: On the commute home I considered ur post further.
It’s not the absolute number of possible “user records” in a database that would give me pause. I’m in no way skilled in the computer / software arts, but even I know a Cray could handle a LOT of them, fast, and not break a sweat. The number of different ways to construct a “user record” is what might get my attention were I an Examiner.
Based on the permutations you presented / suggested, WD and enablement (“overbreadth” in my imprecise slang) might IMO well be implicated.
WD and enablement are of course case specific (IMO few things in patent law aren’t). Wands gives us 6 (or 8?) factors for the later, Ariad confirms the mathematically precise “in possession of the invention” test for the former, and reminds that a US patent is a quid pro quo “deal”. (you get protection for what you fairly disclose and enable). So if “the number of permutations ranks in the thousands” then yea, were I an examiner NOT skilled in the art, I might indeed have a problem with that.
How to distinguish the scenarios? Maybe you suggested it: " looking at millions/billions of widgets at a molecular level, they are all unique." Flaunting my ignorance, I view a “database” as a stored (on spinning reels of magnetic tape) collection of separated binary data. What that collection of 0s and 1s represent (age, height, weight, zipcode …) could be “unique” per se but not really relevant to what is claimed (need to see the rest of the claim). Maybe sometimes a database is just a base (collection) of data, maybe sometimes not, that just gets "massaged" as part of a bigger picture.
OTOH, a “plastic” or a “metal” or a "ceramic" is a composition of matter, inseparable from its individual (albeit possible similar) physical / chemical properties (so say the courts), and such don’t represent anything but themselves. Polystyrene (as in foamed coffee cups) and polycarbonate (as in projectile-resistant glazing) are quite different.
As one who claims to be skilled in this art (chem.), absent some examples or sound prediction, you’d never convince me that if PS works, PC would of course work too. Furthermore, getting back to that claim in the OP, where are the %-ages? 1% to 99% for all?
To cut back to the OP, I see no problem requiring the OP to elect one metal, one plastic, and one ceramic for initial search and examination on the merits. In chem practice, such election does not mean that the allowed claims, if any, will be limited to these species. a generic clai could be held patentable.